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Catherine DAMERVAL

Génétique Quantitative et Évolution - Le Moulon
INRA - Université Paris-Sud - CNRS - AgroParisTech
Ferme du Moulon
F-91190 Gif-sur-Yvette
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Tel +33 (0)1 69 33 23 66

> Position

Senior Researcher (DR2) Centre National de la Recherche Scientifique (CNRS)

Deputy director of UMR Quantitative Genetics & Evolution - Le Moulon

Head of GE2MorF team (Genetics, Epigenetics and Evolution of Floral Morphogenesis)

> Research interests

My current research is in the field of Evolutionary Developmental Genetics (evo-devo). Evo-devo brings additional important complement to the Modern Synthesis theory at least for multicellular organisms, pinpointing the importance of development as a potential source of constraints that interplay with natural selection to produce morphological diversity in the course of evolution.

Since the 2000s, I have been focussing on the evolution of floral traits, namely floral symmetry and petal formation and shape (1 and 2, 4, 6, 8 and 9). I chose these traits because they have evolved several times independently during angiosperm diversification, most probably as a result of convergent selective pressures for pollination efficiency.

Such traits are interesting subjects for evo-devo research, because they provide the opportunity to examine the relative importance of developmental/historical constraints and selection in morphological evolution. The comparative analyses of genes and gene networks in a phylogenetic framework allow the generality of the toolkit and evolutionary tinkering concepts to be appreciated.

External Collaborators on my present research: Sophie Nadot (ESE), Florian Jabbour (MNHN), Etienne Delannoy (URGGV, IPS2), Patrick Laufs (IJPB).

My previous research has also been built on my persistent interest in the genetic and molecular bases of morphological diversity in plants. The underlying hypothesis of my approaches has been that the polymorphism of regulatory factors is of primary importance for morphological evolution.

I have used quantitative proteomics to have an access to the variability of regulatory mechanisms of gene expression in maize and to decipher their genetic architecture (11). I analyzed the molecular polymorphism and diversity of candidate genes in wild and cultivated accessions in the genus Zea, to get an insight into the molecular bases of the response to selection for kernel storage compounds during and after domestication (5, 7). I have also been interested in the evolutionary history of gene families (duplication, gene loss, patterns of selection), some members of which have been found to play important roles in morphological variation (3, 10).

Some past PhD students

Beatriz Gonçalves, Post-Doc IJPB

Florian Jabbour, Research Associate, MNHN Paris

Judith Burstin, Senior Researcher, Institut National de la Recherche Agronomique (INRA)

> Research management

Elected member of CCSU 64-69 (Université Paris-Sud) from 2010.

Member of CSS EGBIP (INRA), 2011-2014.

Member of the section 29 of the National Comitee for Scientific Research (CoNRS) from 2012.

2010-2013: Director of Federal Institute for Research “the Plant and its environment” (IFR87, closed since December 2013)

> Selected publications

  1. Damerval C., Citerne H., Conde E Silva N., Deveaux Y., Delannoy E., Joets J., Simonnet F., Staedler Y., Schonenberger J., Yansouni J., Le Guilloux M., Sauquet H. and Nadot S. (2019) Unraveling the Developmental and Genetic Mechanisms Underpinning Floral Architecture in Proteaceae. Front Plant Sci, 10 18.
  2. Damerval C., Ben Othman W., Manicacci D., Jabbour F. (2018) Distribution area of the two floral morphs of Nigella damascena L. (Ranunculaceae): A diachronic study using herbarium specimens collected in France. Bot Lett, 165 (3-4) 396-403.
  3. Citerne H. L., Reyes E., Le Guilloux M., Delannoy E., Simonnet F., Sauquet H., Weston P. H., Nadot S., Damerval C. (2017) Characterization of CYCLOIDEA-like genes in Proteaceae, a basal eudicot family with multiple shifts in floral symmetry. Ann Bot, 119 (3) 367-378.
  4. Damerval C., Nadot S. (2017) Letter to the 21st century botanist: "What is a flower?" 6. The evo-devo of floral symmetry. Bot Lett, 164 (3) 193-196.
  5. Damerval C. and Becker, A. (2017) Genetics of flower development in Ranunculales - a new, basal eudicot model order for studying flower evolution. New Phytol, New Phytol, 2016 (2) 361-366. DOI 10.1111/nph.14401. Review
  6. Cossart G., Sannier J., Sauquet H., Damerval C., Ronse de Craene L., Jabbour F., Nadot S. (2016) Subfamilial and tribal relationships of Ranunculaceae: evidence from eight molecular markers. Plant Syst Evol, 302 (4) 419–431.
  7. Jabbour F., Nadot S., Espinosa F., Damerval C. (2015) Ranunculacean flower terata: Records, a classification, and some clues about floral developmental genetics and evolution. Flora, 217 64-74.
  8. Jabbour F., Udron M., Le Guilloux M., Goncalves B., Manicacci D., Nadot S., Damerval C. (2015) Flower development schedule and AGAMOUS-like gene expression patterns in two morphs of Nigella damascena (Ranunculaceae) differing in floral architecture. Bot J Linn Soc, 178 (4) 608-619.
  9. Sauquet H., Carrive L., Poullain N., Sannier J., Damerval C., Nadot S. (2015) Zygomorphy evolved from disymmetry in Fumarioideae (Papaveraceae, Ranunculales): new evidence from an expanded molecular phylogenetic framework. Ann Bot, 115 (6) 895-914.
  10. Jabbour F, Cossard G, Le Guilloux M, Sannier J, Nadot S, Damerval C. (2014). Specific duplication and dorsoventrally asymmetric expression patterns of Cycloidea-Like Genes in zygomorphic species of Ranunculaceae. PLoS One, 9(4):e95727.
  11. Gonçalves B., Nougué O., Jabbour F., Ridel C., Morin H., Laufs P., Manicacci D., Damerval C. (2013). An Apetala3 homolog controls both petal identity and floral meristem patterning in Nigella damascena L. (Ranunculaceae). The Plant Journal, 76: 223-35.
  12. Citerne HL, Le Guilloux M, Sannier J, Nadot S, Damerval C. (2013). Combining phylogenetic and syntenic analyses for understanding the evolution of TCP ECE genes in Eudicots. PLoS One, 8(9):e74803.
  13. Damerval C., Citerne H., Le Guilloux M., Domenichini S., Dutheil J., Ronse de Craene L., Nadot S. (2013) Asymmetric morphogenetic cues along the transverse plane – shift from disymmetry to zygomorphy in the flower of Fumarioideae. Am J Bot 100: 391-402.
  14. Corbi J., J. Dutheil, C. Damerval, M. Tenaillon, D. Manicacci. (2012). Accelerated evolution and coevolution drove the evolutionary history of AGPase sub-units during angiosperm radiation. Ann. Bot. 109 : 693-708.
  15. Citerne H, Jabbour F, Nadot S, Damerval C. (2010). The evolution of floral symmetry. Adv. Bot. Res. 54: 85-137.
  16. Manicacci D, Camus-Kulandaivelu L, Fourmann M, Arar C, Barrault S, Rousselet A, Femenias N, Consoli L, Francès L, Méchin V, Murigneux A, Prioul JL, Charcosset A, Damerval C. (2009). Epistatic interactions between Opaque2 transcriptional activator and its target gene CyPPDK1 control kernel trait variation in maize. Plant Physiol, 150: 506-520.
  17. Jabbour F, Ronse De Craene LP, Nadot S, Damerval C. (2009). Establishment of zygomorphy on an ontogenic spiral and evolution of perianth in the tribe Delphinieae (Ranunculaceae). Ann Bot, 104: 809-22.
  18. Damerval C et Nadot S. (2007). Evolution of perianth and stamen characteristics with respect to floral symmetry in Ranunculales. Ann. Bot. 100: 631-640.
  19. Chardon F. and C. Damerval (2005). Phylogenomic Analysis of the PEBP Gene Family in Cereals. J. Mol. Evol. 61, 579-590.
  20. Damerval C., Maurice A., Josse J.-M. and D. de Vienne (1994). Quantitative trait loci underlying gene product variation - a novel perspective for analyzing regulation of genome expression. Genetics, 137, 289-301.