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Carrete L., Ksiezopolska E., Pegueroles C., Gomez-Molero E., Saus E., Iraola-Guzman S., Loska D., Bader O., Fairhead C., Gabaldon T. (2018) Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondary Association with Humans. Curr Biol, 28 (1) 15-27 e7.

Gabaldon T., Fairhead C. (2018) Genomes shed light on the secret life of Candida glabrata: not so asexual, not so commensal. Curr Genet, Epub ahead of print. Review.


Bolotin-Fukuhara M. (2017) Thirty years of the HAP2/3/4/5 complex. Biochim Biophys Acta, 1860 (5) 543-559.

Bukreyeva I., Angoulvant A., Bendib I., Gagnard J. C., Bourhis J. H., Dargere S., Bonhomme J., Thellier M., Gachot B., Wyplosz B. (2017) Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin1. Emerg Infect Dis, 23 (6) 1039-1041.

Senghor Y., Guitard J., Angoulvant A., Hennequin C. (2017) Cryptococcal antigen detection in broncho-alveolar lavage fluid. Med Mycol, Epub ahead of print.


Angoulvant A., Guitard J., Hennequin C. (2016) Old and new pathogenic Nakaseomyces species: epidemiology, biology, identification, pathogenicity and antifungal resistance. FEMS Yeast Res, 16 (2)

Bolotin-Fukuhara M., Fairhead C. (2016) Editorial: Candida glabrata, the other yeast pathogen. FEMS Yeast Res, 16 (2).

Bougnoux M. E., Dannaoui E., Accoceberry I., Angoulvant A., Bailly E., Botterel F., Chevrier S., Chouaki T., Cornet M., Dalle F., Datry A., Dupuis A., Fekkar A., Gangneux J. P., Guitard J., Hennequin C., LeGovic Y., Le Pape P., Maubon D., Ranque S., Sautour M., Sendid B., Chandenier J. (2016) Multicenter comparison of the Etest(R) and EUCAST for antifungal susceptibility testing of Candida isolates to micafungin. Antimicrob Agents Chemother, 60 (8) 5088-91.

Legrand J., Bolotin-Fukuhara M., Bourgais A., Fairhead C., Sicard D. (2016) Life-history strategies and carbon metabolism gene dosage in the Nakaseomyces yeasts. FEMS Yeast Res, 16 (2)

Levy M., Pham L. L., Faye A., de Suremain N., Rambaud J., Angoulvant A., Miatello J., Dauger S., Naudin J. (2016) Parenteral Artesunate for Severe Imported Plasmodium falciparum Malaria in Children. Pediatr Infect Dis J, 35 (9) 1053-4


Angoulvant A., Stern J. B., Wittnebel S., Bourhis J. H., Gachot B., Vittecoq D., Wyplosz B. (2015) Photo quiz. Dyspnea and fever in an allogeneic stem cell recipient. Clin Infect Dis, 60 (1) 100, 157-8.

Badouin H., Hood M. E., Gouzy J., Aguileta G., Siguenza S., Perlin M. H., Cuomo C. A., Fairhead C., Branca A., Giraud T. (2015) Chaos of Rearrangements in the Mating-Type Chromosomes of the Anther-Smut Fungus Microbotryum lychnidis-dioicae. Genetics, 200 (4) 1275-84.

Boisnard S., Zhou Li Y., Arnaise S., Sequeira G., Raffoux X., Enache-Angoulvant A., Bolotin-Fukuhara M., Fairhead C. (2015) Efficient Mating-Type Switching in Candida glabrata Induces Cell Death. PLoS One, 10 (10) e0140990.

de Brevern A. G., Meyniel J. P., Fairhead C., Neuveglise C., Malpertuy A. (2015) Trends in IT Innovation to Build a Next Generation Bioinformatics Solution to Manage and Analyse Biological Big Data Produced by NGS Technologies. Biomed Res Int, 2015 904541. Review.

Guitard J., Atanasova R., Brossas J. Y., Meyer I., Gits M., Marinach C., Vellaissamy S., Angoulvant A., Mazier D., Hennequin C. (2015) Candida inconspicua and Candida norvegensis: new insights into identification in relation to sexual reproduction and genome organization. J Clin Microbiol, 53 (5) 1655-61.

Jaureguiberry S., Thellier M., Ndour P. A., Ader F., Roussel C., Sonneville R., Mayaux J., Matheron S., Angoulvant A., Wyplosz B., Rapp C., Pistone T., Lebrun-Vignes B., Kendjo E., Danis M., Houze S., Bricaire F., Mazier D., Buffet P., Caumes E. (2015) Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, France, 2011-2013. Emerg Infect Dis, 21 (5) 804-12.

Lanternier F., Barbati E., Meinzer U., Liu L., Pedergnana V., Migaud M., Heritier S., Chomton M., Fremond M. L., Gonzales E., Galeotti C., Romana S., Jacquemin E., Angoulvant A., Bidault V., Canioni D., Lachenaud J., Mansouri D., Mahdaviani S. A., Adimi P., Mansouri N., Jamshidi M., Bougnoux M. E., Abel L., Lortholary O., Blanche S., Casanova J. L., Picard C., Puel A. (2015) Inherited CARD9 deficiency in 2 unrelated patients with invasive Exophiala infection. J Infect Dis, 211 (8) 1241-50.

Rivet-Danon D., Guitard J., Grenouillet F., Gay F., Ait-Ammar N., Angoulvant A., Marinach C., Hennequin C. (2015) Rapid diagnosis of cryptococcosis using an antigen detection immunochromatographic test. J Infect, 70 (5) 499-503.



Avant l'intégration à GQE - Le Moulon

Gabaldón, T., Martin, T., Marcet-Houben, M., Durrens, P., Bolotin-Fukuhara, M., Lespinet, O., Aguileta, G., Arnaise, S., Atanassova, R., Boisnard, S., Bouchier, C., Couloux, A., Creno, S., Almeida Cruz, J., Devillers, H., Enache-Angoulvant, A., Guitard, J., Jaouen, L., Ma, L., Marck, C., Neuvéglise, C., Pelletier, E., Poulain, J., Recoquillay, J., Westhof, E., Wincker, P., Dujon, B., Hennequin, C., Fairhead, C. (2013) Comparative genomics of emerging pathogens in the Candida glabrata clade. BMC Genomics, 14:623. Recommended in "Faculty of 1000" .

Atanasova R, Angoulvant A, Tefit M, Gay F, Guitard J, Mazier D, Fairhead C, Hennequin C. (2013) A Mouse Model for Candida glabrata Hematogenous Disseminated Infection Starting from the Gut : Evaluation of Strains with Different Adhesion Properties. PLoS One. 8(7):e69664.

Guitard J., Angoulvant A., Letscher-Bru V., L’ollivier C., Cornet M., Dalle F., Grenouillet F., Lacroix C., Vekhoff A., Maury E., Caillot D., Charles P.E., Pili-Floury S., Herbrecht R., Raffoux E., Brethon B., Hennequin C. (2013). Invasive infections due to Candida norvegensis and Candida inconspicua : report of 12 cases and review of the literature. Med. Mycol.

Montanari, A., Zhou, Y.F., D’Orsi, M.F., Bolotin-Fukuhara, M., Frontali, L., and Francisci, S. (2013). Analyzing the suppression of respiratory defects in the yeast model of human mitochondrial tRNA diseases. Gene .

Green, B., Bouchier, C., Fairhead, C., Craig, N.L., and Cormack, B.P. (2012). Insertion site preference of Mu, Tn5, and Tn7 transposons. Mob DNA 3, 3.

Louis, V.L., Despons, L., Friedrich, A., Martin, T., Durrens, P., Casarégola, S., Neuvéglise, C., Fairhead, C., Marck, C., Cruz, J.A., Straub, M.L., Kugler, V., Sacerdot, C., Uzunov, Z., Thierry, A., Weiss, S., Bleykasten, C., De Montigny, J., Jacques, N., Jung, P., Lemaire, M., Mallet, S., Morel, G., Richard, G.F., Sarkar, A., Savel, G., Schacherer, J., Seret, M.L., Talla, E., Samson, G., Jubin, C., Poulain, J., Vacherie, B., Barbe, V., Pelletier, E., Sherman, D.J., Westhof, E., Weissenbach, J., Baret, P.V., Wincker, P., Gaillardin, C., Dujon, B., Souciet, J.L.(2012). Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization. G3 (Bethesda) 2, 299–311.

Toueille, M., Mirabella, B., Guérin, P., Bouthier de la Tour, C., Boisnard, S., Nguyen, H.H., Blanchard, L., Servant, P., de Groot, A., Sommer, S., et al. (2012). A comparative proteomic approach to better define Deinococcus nucleoid specificities. J Proteomics 75, 2588–2600.

Abdelmoula-Souissi, S., Delahodde, A., Bolotin-Fukuhara, M., Gargouri, A., and Mokdad-Gargouri, R. (2011). Cellular localization of human p53 expressed in the yeast Saccharomyces cerevisiae : effect of NLSI deletion. Apoptosis 16, 746–756.

Bouthier de la Tour, C., Boisnard, S., Norais, C., Toueille, M., Bentchikou, E., Vannier, F., Cox, M.M., Sommer, S., and Servant, P. (2011). The deinococcal DdrB protein is involved in an early step of DNA double strand break repair and in plasmid transformation through its single-strand annealing activity. DNA Repair (Amst.) 10, 1223–1231.

Billiard, S., López-Villavicencio, M., Devier, B., Hood, M.E., Fairhead, C., and Giraud, T. (2011). Having sex, yes, but with whom ? Inferences from fungi on the evolution of anisogamy and mating types. Biol Rev Camb Philos Soc 86, 421–442.

Develoux, M., Enache-Angoulvant, A., Gounant, V., Brian, E., Khalil, A., Bazelly, B., and Hennequin, C. (2011). Hepatic and pulmonary cystic echinococcosis in a patient from the Central African Republic. Travel Med Infect Dis 9, 88–90.

Enache-Angoulvant, A., Guitard, J., Grenouillet, F., Martin, T., Durrens, P., Fairhead, C., and Hennequin, C. (2011). Rapid discrimination between Candida glabrata, Candida nivariensis, and Candida bracarensis by use of a singleplex PCR. J. Clin. Microbiol. 49, 3375–3379.

Magne D, Angoulvant A, Botterel F, Bouges-Michel C, Bougnoux ME, Bouree P, Chochillon C, Cornet M, Dannaoui E, Fekkar A, Galeazzi G, Yera H, Sarfati C, Roux P. (2011). Pneumocystosis : a network survey in the Paris area 2003-2008. Eur J Clin Microbiol Infect Dis. 30:673-5.

Muller, H., Thierry, A., Coppée, J.-Y., Gouyette, C., Hennequin, C., Sismeiro, O., Talla, E., Dujon, B., and Fairhead, C. (2009). Genomic polymorphism in the population of Candida glabrata : gene copy-number variation and chromosomal translocations. Fungal Genet. Biol. 46, 264–276.

Peraza-Reyes, L., Arnaise, S., Zickler, D., Coppin, E., Debuchy, R., and Berteaux-Lecellier, V. (2011). The importomer peroxins are differentially required for peroxisome assembly and meiotic development in Podospora anserina : insights into a new peroxisome import pathway. Mol. Microbiol. 82, 365–377.

Petit A, Levine E, Epaud R, Le Pointe HD, Angoulvant A. (2011). Scopulariopsis brevicaulis abscess in a child treated for myeloblastic leukaemia. Lancet Infect Dis.11:416.

Enache-Angoulvant, A., Torti, F., Tassart, M., Poirot, J.-L., Jafari, A., Roux, P., and Hennequin, C. (2010). Candidal abscess of the parotid gland due to Candida glabrata : report of a case and literature review. Med. Mycol. 48, 402–405.

Enache-Angoulvant, A., Bourget, M., Brisse, S., Stockman-Pannier, C., Diancourt, L., François, N., Rimek, D., Fairhead, C., Poulain, D., and Hennequin, C. (2010). Multilocus microsatellite markers for molecular typing of Candida glabrata : application to analysis of genetic relationships between bloodstream and digestive system isolates. J. Clin. Microbiol. 48, 4028–4034.

ANOFEL Cryptosporidium National Network (Enache-Angoulvant, A. ). (2010). Laboratory-based surveillance for Cryptosporidium in France, 2006-2009. Euro Surveill. 15:19642.

Bouchier, C., Ma, L., Créno, S., Dujon, B., and Fairhead, C. (2009). Complete mitochondrial genome sequences of three Nakaseomyces species reveal invasion by palindromic GC clusters and considerable size expansion. FEMS Yeast Res. 9, 1283–1292.

Boisnard, S., Espagne, E., Zickler, D., Bourdais, A., Riquet, A.-L., and Berteaux-Lecellier, V. (2009). Peroxisomal ABC transporters and beta-oxidation during the life cycle of the filamentous fungus Podospora anserina. Fungal Genet. Biol. 46, 55–66.

Boisnard, S., Lagniel, G., Garmendia-Torres, C., Molin, M., Boy-Marcotte, E., Jacquet, M., Toledano, M.B., Labarre, J., and Chédin, S. (2009). H2O2 activates the nuclear localization of Msn2 and Maf1 through thioredoxins in Saccharomyces cerevisiae. Eukaryotic Cell 8, 1429–1438.

Brisse, S., Pannier, C., Angoulvant, A., de Meeus, T., Diancourt, L., Faure, O., Muller, H., Peman, J., Viviani, M.A., Grillot, R., et al. (2009). Uneven distribution of mating types among genotypes of Candida glabrata isolates from clinical samples. Eukaryotic Cell 8, 287–295.

Enache-Angoulvant, A., Girard, A., Poirot, J.L., and Hennequin, C. (2009). In vitro activity of caspofungin and voriconazole against uncommon Candida spp. Int. J. Antimicrob. Agents 33, 595–596.

Fischer, G., Thompson, D., Wortman, J.R., and Fairhead, C. (2009). Unraveling the genomic diversity of small eukaryotes. Genome Biol. 10, 318.

Génolevures Consortium, Souciet, J.L., Dujon, B., Gaillardin, C., Johnston, M., Baret, P.V., Cliften, P., Sherman, D.J., Weissenbach, J., Westhof, E., Wincker, P., Jubin, C., Poulain, J., Barbe, V., Ségurens, B., Artiguenave, F., Anthouard, V., Vacherie, B., Val, M.E., Fulton, R.S., Minx, P., Wilson, R., Durrens, P., Jean, G., Marck, C., Martin, T., Nikolski, M., Rolland, T., Seret, M.L., Casarégola, S., Despons, L., Fairhead, C., Fischer, G., Lafontaine, I., Leh, V., Lemaire, M., de Montigny, J., Neuvéglise, C., Thierry, A., Blanc-Lenfle, I., Bleykasten, C., Diffels, J., Fritsch, E., Frangeul, L., Goëffon, A., Jauniaux, N., Kachouri-Lafond, R., Payen, C., Potier, S., Pribylova, L., Ozanne, C., Richard, G.F., Sacerdot, C., Straub, M.L., Talla, E. (2009). Comparative genomics of protoploid Saccharomycetaceae. Genome Res. 19, 1696–1709.

Kachouri-Lafond, R., Dujon, B., Gilson, E., Westhof, E., Fairhead, C., and Teixeira, M.T. (2009). Large telomerase RNA, telomere length heterogeneity and escape from senescence in Candida glabrata. FEBS Lett. 583, 3605–3610.

De Luca, C., Zhou, Y., Montanari, A., Morea, V., Oliva, R., Besagni, C., Bolotin-Fukuhara, M., Frontali, L., and Francisci, S. (2009). Can yeast be used to study mitochondrial diseases ? Biolistic tRNA mutants for the analysis of mechanisms and suppressors. Mitochondrion 9, 408–417.

Reboutier, D., Piednoël, M., Boisnard, S., Conti, A., Chevalier, V., Florent, M., Gibot-Leclerc, S., Da Silva, B., Chastin, C., Fallague, K., et al. (2009). Combination of different molecular mechanisms leading to fluconazole resistance in a Candida lusitaniae clinical isolate. Diagn. Microbiol. Infect. Dis. 63, 188–193.

Arnaise, S., Zickler, D., Bourdais, A., Dequard-Chablat, M., and Debuchy, R. (2008). Mutations in mating-type genes greatly decrease repeat-induced point mutation process in the fungus Podospora anserina. Fungal Genet. Biol. 45, 207–220.

Boisnard, S., Ruprich-Robert, G., Florent, M., Da Silva, B., Chapeland-Leclerc, F., and Papon, N. (2008). Insight into the role of HOG pathway components Ssk2p, Pbs2p, and Hog1p in the opportunistic yeast Candida lusitaniae. Eukaryotic Cell 7, 2179–2183.

Boisnard, S., Ruprich-Robert, G., Florent, M., Da Silva, B., Chapeland-Leclerc, F., and Papon, N. (2008). Role of Sho1p adaptor in the pseudohyphal development, drugs sensitivity, osmotolerance and oxidant stress adaptation in the opportunistic yeast Candida lusitaniae. Yeast 25, 849–859.

Espagne, E., Lespinet, O., Malagnac, F., Da Silva, C., Jaillon, O., Porcel, B.M., Couloux, A., Aury, J.M., Ségurens, B., Poulain, J., Anthouard, V., Grossetete, S., Khalili, H., Coppin, E., Déquard-Chablat, M., Picard, M., Contamine, V., Arnaise, S., Bourdais, A., Berteaux-Lecellier, V., Gautheret, D., de Vries, R.P., Battaglia, E., Coutinho, P.M., Danchin, E.G., Henrissat, B., Khoury, R.E., Sainsard-Chanet, A., Boivin, A., Pinan-Lucarré, B., Sellem, C.H., Debuchy, R., Wincker, P., Weissenbach, J., Silar, P. (2008). The genome sequence of the model ascomycete fungus Podospora anserina. Genome Biol. 9, R77.

Muller, H., Hennequin, C., Gallaud, J., Dujon, B., and Fairhead, C. (2008). The asexual yeast Candida glabrata maintains distinct a and alpha haploid mating types. Eukaryotic Cell 7, 848–858.

Ruprich-Robert, G., Chapeland-Leclerc, F., Boisnard, S., Florent, M., Bories, G., and Papon, N. (2008). Contributions of the response regulators Ssk1p and Skn7p in the pseudohyphal development, stress adaptation, and drug sensitivity of the opportunistic yeast Candida lusitaniae. Eukaryotic Cell 7, 1071–1074.

Publications récentes des membres de l’équipe sur d’autres thématiques

Bolotin-Fukuhara M, Dumas B and Gaillardin C, (2010), Yeasts as a model for human diseases, FEMS Yeast Res, 10(8):959-60

Rinaldi T, Dallabona C, Ferrero I, Frontali L and Bolotin-Fukuhara M, (2010), Mitochondrial diseases and the role of the yeast models, FEMS Yeast Res, 10(8):1006-22

Sybirna K, Petryk N, Zhou YF, Sibirny A and Bolotin-Fukuhara M, (2010), A novel Hansenula polymorpha transcriptional factor HpHAP4-B, able to functionally replace the S. cerevisiae HAP4 gene, contains an additional bZip motif, Yeast, 27(11):941-54

Fang ZA, Wang GH, Chen AL, Li YF, Liu JP, Li YY, Bolotin-Fukuhara M and Bao WG, (2009), Gene responses to oxygen availability in Kluyveromyces lactis : an insight on the evolution of the oxygen-responding system in yeast, PLoS One 4(10) : e7561

Bao WG, Guiard B, Fang Z, Donnini C, Gervais M, Lopes Passos FM, Ferrero I, Fukuhara H, Bolotin-Fukuhara M, Oxygen-dependant transcriptional regulator Hap1p limits glucose uptake by repressing the expression of the major glucose transporter gene RAG1 in Kluyveromyces lactis, Eukaryotic Cell 7(11) : 1895-905

Archer CT, Delahodde A, Gonzalez F, Johnston SA, Kodadek T, (2008), Activation domain-dependent mono-ubiquitylation of gal4 protein is essential for promoter binding in vivo, J Biol Chem. 283(18) : 12614-23

Eijssen LM, Lindsey PJ, Peeters R, Westra RL, van Eijsden RG, Bolotin-Fukuhara M, Smeets HJ, Vlietinck RF, (2008), A novel stepwise analysis procedure of genome-wide expression profiles identifies transcript signatures of thiamine genes as classifiers of mitochondrial mutants, Yeast 25 (2) : 129-40

Montanari A, Besagni C, De Luca C, Morea V, Oliva R, Tramontano A, Bolotin-Fukuhara M, Frontali L, Francisci S, (2008), Yeast as a model of human mitochondrial tRNA base substitutions : Investigation of the molecular basis of respiratory defects, RNA, 14(2) : 275-83

Farina F, Alberti A, Breuil N, Bolotin-Fukuhara M, Pinto M, Culetto E, (2008), Differential expression pattern of the four mitochondrial adenine nucleotide translocator genes ant and their roles during the development of Caenorhabditis elegans, Developmental Dynamics, 237(6) : 1668-1681