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I am interested in understanding the causes of phenotypic variation
within populations, and the (co)evolution of genetic polymorphism and
phenotypic variation.
The french government is now undergoing a deep reform of our research and university system, which I feel dangerous. Behind this link, my plea for the defence of the university (in french).
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Research interests and publications
Phenotypic diversity for life-history traits
Sabarly V, Bouvet O, Glodt J, Clermont O, Skurnik D, Diancourt L, De Vienne D, Denamur E, Dillmann C. (2011) The decoupling between genetic structure and metabolic phenotypes in Escherichia coli leads to continuous phenotypic diversity. J Evol Biol. doi: 10.1111/j.1420-9101.2011.02287.x.
Spor A., C. Dillmann, S. Wang, D. de Vienne, D. Sicard, E. Parent (2010) Hierarchical Bayesian Modelling for Saccharomyces cerevisiae population dynamics. International Journal of Food Microbiology, 142(1-2):25-35.
Johannes F., Porcher E., Teixeira F. K., Saliba-Colombani V., Simon M., Agier N., Bulski A., Albuisson J., Heredia F., Audigier P., Bouchez D., Dillmann C., Guerche P., Hospital F., Colot V. (2009). Assessing the impact of transgenerational epigenetic variation on complex traits. PLoS Genet, 5(6), e1000530.
Spor,A. Wang,S. Dillmann,C. de Vienne,D. Sicard,D. 2008. "Ant" and "grasshopper" life-history strategies in Saccharomyces cerevisiae. PLoS ONE 3 : e1579.
Modelling the relationship between genes and complex traits
Wang S, Spor A, Nidelet T, Montalent P, Dillmann C, de Vienne D, Sicard D. (2011) Switch between life history strategies due to changes in glycolytic enzyme gene dosage in Saccharomyces cerevisiae. Appl Environ Microbiol. 2011 Jan;77(2):452-9.
Julie B. Fiévet, Christine Dillmann, Dominique de Vienne (2010) Systemic properties of metabolic networks lead to an epistasis-based model for heterosis. Theor Appl Genet 120:463-473.
Fiévet J, Dillmann C, Curien G, and de Vienne D, 2006 Simplified
modelling of metabolic pathways for flux prediction and optimization :
lessons from an in vitro reconstruction of the upper part of
glycolysis. Biochem. J. 396: 17-26.
Lion S, Gabriel F, Bost B, Fiévet J, Dillmann C and de Vienne D, 2004
An extension to the metabolic control theory taking into account
correlations between enzyme concentrations. Eur. J. Biochem
271 :1-17.
FIEVET, J., LAGNIEL, G., DILLMANN C., DAVANTURE, M., ,LABARRE J., and
de VIENNE D., 2004 Assessing factors for reliable quantitative
proteomics based on two-dimensional electrophoresis. Proteomics, 4,
1939-1949.
de Vienne D., Bost B., Fiévet J., Zivy M., and Dillmann C.,2001
Variabilité d'expression du proteome et heterosis. C.R. Acad. Agric.
Fr. 87: 27-38
De VIENNE D., B. BOST, J. FIEVET and C. DILLMANN, 2001 Optimization of
enzyme concentrations for unbranched reaction chains: the concept of
combined response coefficient. Acta Biotheoretica 49: 341-350.
De VIENNE D., B. BOST, J. FIEVET, M. ZIVY and C. DILLMANN, 2001 Genetic
variability of proteome expression and metabolic control. Plant
Physiol. Biochem. 39:1-13.
BOST B., D. DE VIENNE, F. HOSPITAL, L. MOREAU, and C. DILLMANN, 2001
Genetic and non genetic bases for the L-shaped distribution of QTL
effects. Genetics 157 :1773-1787.
BOST B., C. DILLMANN and D. DE VIENNE, 1999 Fluxes and metabolic pools
as model traits for quantitative genetics. I The L-shaped distribution
of gene effects. Genetics 153: 2001-2012.
DILLMANN C. and J.L. FOULLEY, 1998 Another look at multiplicative models in quantitative genetics. Gen. Sel. Evol. 30:543-564.
Neutral versus selected diversity within and between populations
Durand E., M.I. Tenaillon, C. Ridel, D. Coubriche, P. Jamin, S. Jouanne, A. Ressayre, A. Charcosset, C. Dillmann (2010) Standing variation and new mutations
both contribute to a fast response to selection for flowering time in
maize inbreds. BMC Evolutionary Biology 10:2.
Albertin W., Marullo P., Aigle M., Bourgais A., Bely M., Dillmann C., de Vienne D. and Sicard D. (2009) Evidence for autotetraploidy associated with reproductive isolation in Saccharomyces cerevisiae: towards a new domesticated species. J. Evol. Biol. 22(11):2157-70.
Edelist C., Raffoux X., Falque M., Dillmann C., Sicard D., Rieseberg L. H., Karrenberg S. (2009) Differential expression of candidate salt-tolerance genes in the halophyte Helianthus paradoxus and its glycophyte progenitors H. annuus and H. petiolaris (Asteraceae). Am. J. Bot. 96 1830-1838.
EDELIST C, LEXER C, DILLMANN C, SICARD D, RIESEBERG LH (2006)
Microsatellite signature of ecological selection for salt tolerance in
a wild sunflower hybrid species, Helianthus paradoxus. Molecular
Ecology 15(14): 4623
DEGEN T., C. DILLMANN, F. MARION-POLL and T. TURLINGS, 2004 High
genetic variability of herbivore-induced volatile emission within a
broad range of maize inbred lines. Plant Physiology
135 :1928-1938.
ROLDAN-RUIZ I., F.A. VAN EUWIJK, T.J. GILLILAND, P. DUBREUIL, C.
DILLMANN, J. LALLEMAND, M. De LOOSE, C.P. BARIL, 2001 A comparative
study of molecular and morphological methods of describing
relationships between perennial ryegrass (Lolium perenne L.) varieties.
Theoretical and Applied Genetics 103 : 1138-1150.
DILLMANN C. and D. GUERIN, 1998 Comparison between maize inbred lines :
genetic distances in the expert�s eye. Agronomie 18:659-667.
DILLMANN C., A. BAR-HEN, D. GUERIN, A. MURIGNEUX and A. CHARCOSSET,
1997 Comparison of RFLP and morphological distances between maize
inbreds. Consequences for germplasm protection purposes. Theor. Appl.
Genet. 95:92-102.
CIAMPOLINI R., GOUDARZI K., VAIMAN D., DILLMANN C., MAZZANTI E.,
FOULLEY JL., LEVEZIEL H., CIANCI D., 1995 Individual multilocus
genotypes using microsatellite polymorphism to permit the analysis of
genetic variability. J. Anim. Sci. 73:3259-3268.
GARNIER P. and C. DILLMANN, 1992 A computer program for testing
pairwise linkage disequilibria in subdivided populations. Journal of
Heredity 83:3.
Multilocus genotype frequencies
SERVIN B, DILLMANN C, DECOUX G and F. HOSPITAL , 2002 MDM : a program
to compute fully informative genotype frequencies in complex breeding
schemes. J Hered 93: 227-228
HOSPITAL F., C. DILLMANN and A. E. MELCHINGER, 1996 A general algorithm
to compute multilocus genotype frequencies under various mating
systems. Comput. Appl. Biosci. 12(6):455-462.
